Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p164 | (1) | WCRB2014

Obesity depresses Toll-like receptor superfamily members in the ovary

Galvao Antonio , Socha Barbara , Jura Magdalena , Nowialis Pawel , Skarzynski Dariusz

Introduction: Obesity and its associated metabolic disorders lead to ovarian failure and infertility. Nonetheless, the hierarchy of pathways leading to ovarian dysfunction is unknown. Presently, we studied the impact of obesity on ovarian innate immune response and steroidogenesis throughout the time.Materials and methods: An in vivo study was conducted on C57Bl/6J mice (n=8/group) fed a chow-diet versus high-fat diet during 4- (C-4w; H...